By the end of the 18th century it appears that citizens of Anavatos survived in their barren and mountainous village working as lumberjacks – which was their main occupation until recently – and as workers in the Ottoman government they owned the ship yards of the City. The wage of the workers reached in their families through older people of Anavatos that received it from the Municipality of the country.  
The life of the residents was passing by harmoniously until the slaughter of Chios in 1822. Those who survived by the dreary kept the village alive, however the destruction of the earthquake in 1881 sunk the village in bereavement. For the third time the villagers recreated their poor settlement. During the first persecution in 1918 many people arrived from Micra Asia and worked on the cultivation of tobacco. 
Citizens of Anavatos, as it is mentioned before, were very capable lumberjacks. Turks were aware of that and sent them for chore in Alikarnasos. People from Anavatos, in order to be rescued by the chore, abandoned their axes and became priests. They learned certain prayers and earned their living as wandering priests.
The decline that was stretched out in the Medieval Anavatos was caused by the slaughters that Turks made in 1822. On the Thursday before Easter in 1822 the Turks captured, slaughtered and burnt. Citizens of Chios run away in a distant beach of the island with the hope to escape from salvation. Many people tried to find shelter in the abbeys of Ag. Minas and Nea Moni, while others resorted to Anavatos. Likourgos Logothetis was among them.  Likourgos Logothetis came from Samos and conveinced the citizens of Chios to declare the revolution. The 1000 defenders, men, women, children and old men tried to deter the profanation of Anavatos with all their forces. They all fought with courage. The exceptional fortification of the village was actually the main reason  that hold the Turkish attacks. They had no guns; they flew Stones and beehives. People from Samos unfortunately did not help, although they had munitions. In addition to that Likourgos Logothetis, took people from Samos and went down to Elinta, where a boat waited with captain Kefalas, in order to take women and children away from Anavatos. Logothetis in order to save himself and his patriots prevented captain Kefalas from taking people from Anavatos. The next day “Monday of Thomas”, Turks "destroyed the place" during their second attack (the first had failed). Turks slaughtered without any mercy women and children, apart from few who were led to slave markets. Some resorted to the church of Taxiarhis, where they were burnt alive from Turks. Others resorted and fell in the southwestern ravine of village in order to save their honour. The pillages in the churches and the houses had no precedent. 
After the revolution in 1822 many citizens of Anavatos went down in Chios, worked in the shipyards and became coveted craftsmen. The Sultan was so satisfied with them that   abolished all the taxes in the village.